Obesity and cancer: inflammation bridges the two

Obesity and cancer: inflammation bridges the two

Highlights • Obesity is associated with chronic inflammation and chronic diseases. • Obesity is associated with increased risk and progression of several cancers. • The mechanism by which obesity promotes cancer is complex and tissue-specific. • An underlying theme in obesity-associated cancer is in...

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Veröffentlicht in:Current opinion in pharmacology 2016-08, Vol.29, p.77-89
Hauptverfasser: Kolb, Ryan, Sutterwala, Fayyaz S, Zhang, Weizhou
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Animals
Body Weight
Disease Progression
Humans
Inflammation - complications
Inflammation - immunology
Inflammation - pathology
Internal Medicine
Medical Education
Neoplasms - immunology
Neoplasms - pathology
Neoplasms - therapy
Obesity - complications
Obesity - epidemiology
Obesity - immunology
United States - epidemiology
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Beschreibung
Zusammenfassung:Highlights • Obesity is associated with chronic inflammation and chronic diseases. • Obesity is associated with increased risk and progression of several cancers. • The mechanism by which obesity promotes cancer is complex and tissue-specific. • An underlying theme in obesity-associated cancer is inflammation.
ISSN:1471-4892
1471-4973
DOI:10.1016/j.coph.2016.07.005