Necrosis of the pancreas in the haemolytic uraemic syndrome

A case of haemolytic uraemic syndrome in a three year old boy is described. The clinical course was complicated by hyperglycaemia, and biochemical assay of plasma showed an almost total lack of pancreatic insulin. Extensive necrosis of the exocrine and endocrine pancreas was found at necropsy. The p...

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Veröffentlicht in:	Journal of clinical pathology 1984-06, Vol.37 (6), p.655-658
Hauptverfasser:	Primhak, R A, Taitz, L S, Variend, S, Webb, D H, Cser, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemias. Hemoglobinopathies Biological and medical sciences Child, Preschool Diseases of red blood cells Hematologic and hematopoietic diseases Hemolytic-Uremic Syndrome - complications Hemolytic-Uremic Syndrome - pathology Humans Hyperglycemia - complications Insulin - metabolism Islets of Langerhans - metabolism Islets of Langerhans - pathology Male Medical sciences Necrosis Pancreas - metabolism Pancreas - pathology
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Beschreibung
Zusammenfassung:	A case of haemolytic uraemic syndrome in a three year old boy is described. The clinical course was complicated by hyperglycaemia, and biochemical assay of plasma showed an almost total lack of pancreatic insulin. Extensive necrosis of the exocrine and endocrine pancreas was found at necropsy. The possible pathological physiology of this complication and its prognostic importance are discussed.
ISSN:	0021-9746 1472-4146
DOI:	10.1136/jcp.37.6.655