Cryptococcal Meningitis Presenting as a Complication in HIV-infected Children: A Case Series From Sub-Saharan Africa

Cryptococcal meningitis is a leading infectious disease worldwide as a result of the high burden of HIV and AIDS, although its cumulative incidence is very low in children compared with that in adults. Very few studies involving the disease in children have been reported including sub-Saharan Africa...

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Veröffentlicht in:	The Pediatric infectious disease journal 2016-09, Vol.35 (9), p.979-980
Hauptverfasser:	Nyazika, Tinashe K, Masanganise, Faith, Hagen, Ferry, Bwakura-Dangarembizi, Mutsawashe F, Ticklay, Ismail M H, Robertson, Valerie J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Africa South of the Sahara AIDS-Related Opportunistic Infections - diagnosis AIDS-Related Opportunistic Infections - drug therapy AIDS-Related Opportunistic Infections - epidemiology Anti-Retroviral Agents - therapeutic use Child HIV Infections - complications Humans Male Meningitis, Cryptococcal - diagnosis Meningitis, Cryptococcal - drug therapy Meningitis, Cryptococcal - epidemiology Retrospective Studies
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Beschreibung
Zusammenfassung:	Cryptococcal meningitis is a leading infectious disease worldwide as a result of the high burden of HIV and AIDS, although its cumulative incidence is very low in children compared with that in adults. Very few studies involving the disease in children have been reported including sub-Saharan Africa, with the highest prevalence of HIV-infected children in the world. We summarize 5 cases of children diagnosed with cryptococcal meningitis at a tertiary hospital in Harare, Zimbabwe, between October 1, 2013, and September 30, 2014.
ISSN:	0891-3668 1532-0987
DOI:	10.1097/INF.0000000000001212