Hypertension and risk of prostate cancer: a systematic review and meta-analysis

Hypertension and risk of prostate cancer: a systematic review and meta-analysis

The previously reported association between hypertension and prostate cancer risk was controversial. We performed this systematic review and meta-analysis of all available studies to summarize evidence on this association. Studies were identified by searching PubMed, Web of Science and Chinese Natio...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Scientific reports 2016-08, Vol.6 (1), p.31358-31358, Article 31358
Hauptverfasser: Liang, Zhen, Xie, Bo, Li, Jiangfeng, Wang, Xiao, Wang, Song, Meng, Shuai, Ji, Alin, Zhu, Yi, Xu, Xin, Zheng, Xiangyi, Xie, Liping
Format: Artikel
Sprache:eng
Schlagworte:
631/67/2324
692/4025/1752
Health risk assessment
Humanities and Social Sciences
Hypertension
Meta-analysis
multidisciplinary
Prostate cancer
Risk assessment
Science
Statistical analysis
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The previously reported association between hypertension and prostate cancer risk was controversial. We performed this systematic review and meta-analysis of all available studies to summarize evidence on this association. Studies were identified by searching PubMed, Web of Science and Chinese National Knowledge Infrastructure (CNKI) databases through January 2016. Pooled relative risks (RRs) with their corresponding 95% confidence intervals (CIs) were calculated using a random-effects model. A total of 21 published studies were included in this meta-analysis. A significant increase in the risk of prostate cancer (RR 1.08, 95% CI 1.02–1.15, P  = 0.014) was observed among individuals with hypertension. There was statistically significant heterogeneity among included studies ( P  
ISSN:2045-2322
2045-2322
DOI:10.1038/srep31358