Hepatotoxicity due to zinc phosphide poisoning in two patients: role of N‐acetylcysteine

Key Clinical Message Zinc phosphide (Zn3P2/ZnP) is used as a rodenticide. The most common signs of toxicity are nausea, vomiting, hypotension, and metabolic acidosis; patients presenting such signs are referred to the emergency department (ED) of the hospitals. Therefore, this study aimed to report...

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Veröffentlicht in:Clinical case reports 2016-08, Vol.4 (8), p.768-772
Hauptverfasser: Oghabian, Zohreh, Afshar, Arefeh, Rahimi, Hamid Reza
Format: Artikel
Sprache:eng
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Zusammenfassung:Key Clinical Message Zinc phosphide (Zn3P2/ZnP) is used as a rodenticide. The most common signs of toxicity are nausea, vomiting, hypotension, and metabolic acidosis; patients presenting such signs are referred to the emergency department (ED) of the hospitals. Therefore, this study aimed to report two cases of hepatotoxicity following accidental and intentional ZnP poisoning and successful management with N‐acetylcysteine (NAC). Zinc phosphide (Zn3P2/ZnP) is used as a rodenticide. The most common signs of toxicity are nausea, vomiting, hypotension, and metabolic acidosis; patients presenting such signs are referred to the emergency department (ED) of the hospitals. Therefore, this study aimed to report two cases of hepatotoxicity following accidental and intentional ZnP poisoning and successful management with N‐acetylcysteine (NAC).
ISSN:2050-0904
2050-0904
DOI:10.1002/ccr3.618