Distribution of IgG galactosylation as a promising biomarker for cancer screening in multiple cancer types
Dear Editor, Cancer is prevalent worldwide. Currently, most routinely used non-invasive serological cancer biomarkers, including carcino-embryonic antigen （CEA）, prostate-specific antigen （PSA）, α-fetoprotein （AFP）, CA125, CA15-3, and CA19-9, suffer from low specificity and/ or low sensitivity [1]....
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| Veröffentlicht in: | Cell research 2016-08, Vol.26 (8), p.963-966 |
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| container_title | Cell research |
| container_volume | 26 |
| creator | Ren, Shifang Zhang, Zejian Xu, Congjian Guo, Lin Lu, Renquan Sun, Yihong Guo, Jianming Qin, Ruihuan Qin, Wenjun Gu, Jianxin |
| description | Dear Editor, Cancer is prevalent worldwide. Currently, most routinely used non-invasive serological cancer biomarkers, including carcino-embryonic antigen （CEA）, prostate-specific antigen （PSA）, α-fetoprotein （AFP）, CA125, CA15-3, and CA19-9, suffer from low specificity and/ or low sensitivity [1]. Improvements in timely and effective diagnosis of cancer are urgently needed. |
| doi_str_mv | 10.1038/cr.2016.83 |
| format | Article |
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Currently, most routinely used non-invasive serological cancer biomarkers, including carcino-embryonic antigen （CEA）, prostate-specific antigen （PSA）, α-fetoprotein （AFP）, CA125, CA15-3, and CA19-9, suffer from low specificity and/ or low sensitivity [1]. Improvements in timely and effective diagnosis of cancer are urgently needed.</description><identifier>ISSN: 1001-0602</identifier><identifier>EISSN: 1748-7838</identifier><identifier>DOI: 10.1038/cr.2016.83</identifier><identifier>PMID: 27364686</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>631/67/1857 ; 631/67/2322 ; 631/80/458/1524 ; Biomarkers, Tumor - blood ; Biomarkers, Tumor - chemistry ; Biomedical and Life Sciences ; Cell Biology ; Cohort Studies ; Early Detection of Cancer - methods ; Female ; Galactose - metabolism ; Glycosylation ; Humans ; IgG ; Immunoglobulin G - blood ; Immunoglobulin G - chemistry ; Immunoglobulin G - immunology ; Letter to the Editor ; Life Sciences ; Male ; Neoplasms - blood ; Neoplasms - diagnosis ; Neoplasms - immunology ; 特异性抗原 ; 生物标志物 ; 癌症 ; 筛查 ; 类型 ; 糖分 ; 肿瘤标志物</subject><ispartof>Cell research, 2016-08, Vol.26 (8), p.963-966</ispartof><rights>The Author(s) 2016</rights><rights>Copyright Nature Publishing Group Aug 2016</rights><rights>Copyright © 2016 The Author(s) 2016 The Author(s)</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c502t-841c2f299da5ac63680cf4ca36811e3d320f8331627316be3a942506c6ee30313</citedby><cites>FETCH-LOGICAL-c502t-841c2f299da5ac63680cf4ca36811e3d320f8331627316be3a942506c6ee30313</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/85240X/85240X.jpg</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973333/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973333/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,41467,42536,51298,53770,53772</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27364686$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ren, Shifang</creatorcontrib><creatorcontrib>Zhang, Zejian</creatorcontrib><creatorcontrib>Xu, Congjian</creatorcontrib><creatorcontrib>Guo, Lin</creatorcontrib><creatorcontrib>Lu, Renquan</creatorcontrib><creatorcontrib>Sun, Yihong</creatorcontrib><creatorcontrib>Guo, Jianming</creatorcontrib><creatorcontrib>Qin, Ruihuan</creatorcontrib><creatorcontrib>Qin, Wenjun</creatorcontrib><creatorcontrib>Gu, Jianxin</creatorcontrib><title>Distribution of IgG galactosylation as a promising biomarker for cancer screening in multiple cancer types</title><title>Cell research</title><addtitle>Cell Res</addtitle><addtitle>Cell Research</addtitle><description>Dear Editor, Cancer is prevalent worldwide. Currently, most routinely used non-invasive serological cancer biomarkers, including carcino-embryonic antigen （CEA）, prostate-specific antigen （PSA）, α-fetoprotein （AFP）, CA125, CA15-3, and CA19-9, suffer from low specificity and/ or low sensitivity [1]. Improvements in timely and effective diagnosis of cancer are urgently needed.</description><subject>631/67/1857</subject><subject>631/67/2322</subject><subject>631/80/458/1524</subject><subject>Biomarkers, Tumor - blood</subject><subject>Biomarkers, Tumor - chemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Cell Biology</subject><subject>Cohort Studies</subject><subject>Early Detection of Cancer - methods</subject><subject>Female</subject><subject>Galactose - metabolism</subject><subject>Glycosylation</subject><subject>Humans</subject><subject>IgG</subject><subject>Immunoglobulin G - blood</subject><subject>Immunoglobulin G - chemistry</subject><subject>Immunoglobulin G - immunology</subject><subject>Letter to the Editor</subject><subject>Life Sciences</subject><subject>Male</subject><subject>Neoplasms - blood</subject><subject>Neoplasms - diagnosis</subject><subject>Neoplasms - immunology</subject><subject>特异性抗原</subject><subject>生物标志物</subject><subject>癌症</subject><subject>筛查</subject><subject>类型</subject><subject>糖分</subject><subject>肿瘤标志物</subject><issn>1001-0602</issn><issn>1748-7838</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqNkUFv1DAQhS0Eou3ChR-AIrhUoCxjj-M4l0qoQKlUiQucLa_XSb1k7dROkPbf43S3q4I44ItHfp-f33gIeUVhSQHlBxOXDKhYSnxCTmnNZVlLlE9zDUBLEMBOyFlKGwBW8Yo-JyesRsGFFKdk88mlMbrVNLrgi9AW191V0elemzGkXa_vj3UqdDHEsHXJ-a5YubDV8aeNRRtiYbQ3uUwmWutn2fliO_WjG3r7II67waYX5Fmr-2RfHvYF-fHl8_fLr-XNt6vry483pamAjaXk1LCWNc1aV9oIFBJMy43OBaUW18iglYhU5CaoWFnUDWcVCCOsRUCKC3Kx9x2m1daujfVj1L0aosupdypop_5UvLtVXfileFPjvBbk_GAQw91k06hy48b2vfY2TEnRHERKbFD-BwpSQM24yOjbv9BNmKLPP3FPAecN45l6t6dMDClF2x5zU1DztJWJap62knPQ1487PaIP483A-z2QsuQ7Gx-9-S-7N4e3b4Pv7vKFo6OogTUcZYW_AWoBvw0</recordid><startdate>20160801</startdate><enddate>20160801</enddate><creator>Ren, Shifang</creator><creator>Zhang, Zejian</creator><creator>Xu, Congjian</creator><creator>Guo, Lin</creator><creator>Lu, Renquan</creator><creator>Sun, Yihong</creator><creator>Guo, Jianming</creator><creator>Qin, Ruihuan</creator><creator>Qin, Wenjun</creator><creator>Gu, Jianxin</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W94</scope><scope>WU4</scope><scope>~WA</scope><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7QP</scope><scope>7QR</scope><scope>7T5</scope><scope>7TK</scope><scope>7TM</scope><scope>7TO</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20160801</creationdate><title>Distribution of IgG galactosylation as a promising biomarker for cancer screening in multiple cancer types</title><author>Ren, Shifang ; Zhang, Zejian ; Xu, Congjian ; Guo, Lin ; Lu, Renquan ; Sun, Yihong ; Guo, Jianming ; Qin, Ruihuan ; Qin, Wenjun ; Gu, Jianxin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c502t-841c2f299da5ac63680cf4ca36811e3d320f8331627316be3a942506c6ee30313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>631/67/1857</topic><topic>631/67/2322</topic><topic>631/80/458/1524</topic><topic>Biomarkers, Tumor - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Cell research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ren, Shifang</au><au>Zhang, Zejian</au><au>Xu, Congjian</au><au>Guo, Lin</au><au>Lu, Renquan</au><au>Sun, Yihong</au><au>Guo, Jianming</au><au>Qin, Ruihuan</au><au>Qin, Wenjun</au><au>Gu, Jianxin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Distribution of IgG galactosylation as a promising biomarker for cancer screening in multiple cancer types</atitle><jtitle>Cell research</jtitle><stitle>Cell Res</stitle><addtitle>Cell Research</addtitle><date>2016-08-01</date><risdate>2016</risdate><volume>26</volume><issue>8</issue><spage>963</spage><epage>966</epage><pages>963-966</pages><issn>1001-0602</issn><eissn>1748-7838</eissn><abstract>Dear Editor, Cancer is prevalent worldwide. Currently, most routinely used non-invasive serological cancer biomarkers, including carcino-embryonic antigen （CEA）, prostate-specific antigen （PSA）, α-fetoprotein （AFP）, CA125, CA15-3, and CA19-9, suffer from low specificity and/ or low sensitivity [1]. Improvements in timely and effective diagnosis of cancer are urgently needed.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>27364686</pmid><doi>10.1038/cr.2016.83</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | 631/67/1857 631/67/2322 631/80/458/1524 Biomarkers, Tumor - blood Biomarkers, Tumor - chemistry Biomedical and Life Sciences Cell Biology Cohort Studies Early Detection of Cancer - methods Female Galactose - metabolism Glycosylation Humans IgG Immunoglobulin G - blood Immunoglobulin G - chemistry Immunoglobulin G - immunology Letter to the Editor Life Sciences Male Neoplasms - blood Neoplasms - diagnosis Neoplasms - immunology 特异性抗原 生物标志物 癌症 筛查 类型 糖分 肿瘤标志物 |
| title | Distribution of IgG galactosylation as a promising biomarker for cancer screening in multiple cancer types |
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