Treatment and outcome of Ganglioneuroma and Ganglioneuroblastoma intermixed

Ganglioneuroma (GN) and ganglioneuroblastoma intermixed (GNBI) are mature variants of neuroblastic tumors (NT). It is still discussed whether incomplete resection of GN/GNBI impairs the outcome of patients. Clinical characteristics and outcome of localized GN/GNBI were retrospectively compared to lo...

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Veröffentlicht in:	BMC cancer 2016-07, Vol.16 (1), p.542-542, Article 542
Hauptverfasser:	Decarolis, Boris, Simon, Thorsten, Krug, Barbara, Leuschner, Ivo, Vokuhl, Christian, Kaatsch, Peter, von Schweinitz, Dietrich, Klingebiel, Thomas, Mueller, Ingo, Schweigerer, Lothar, Berthold, Frank, Hero, Barbara
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Age of Onset Analysis Care and treatment Case reports Catecholamines Child Child, Preschool Cytotoxicity Disease Progression Drug Therapy - methods Endocrine Surgical Procedures - methods Female Ganglioneuroblastoma - therapy Ganglioneuroma - therapy Histology Humans Infant Infant, Newborn Magnetic resonance imaging Male Metabolites Neoplasm Staging Neuroblastoma Retrospective Studies Surgery Time-to-Treatment Treatment Outcome Tumors Urine
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Zusammenfassung:	Ganglioneuroma (GN) and ganglioneuroblastoma intermixed (GNBI) are mature variants of neuroblastic tumors (NT). It is still discussed whether incomplete resection of GN/GNBI impairs the outcome of patients. Clinical characteristics and outcome of localized GN/GNBI were retrospectively compared to localized neuroblastoma (NB) and ganglioneuroblastoma-nodular (GNBN) registered in the German neuroblastoma trials between 2000 and 2010. Of 808 consecutive localized NT, 162 (20 %) were classified as GN and 55 (7 %) as GNBI. GN/GNBI patients presented more often with stage 1 disease (68 % vs. 37 %, p
ISSN:	1471-2407 1471-2407
DOI:	10.1186/s12885-016-2513-9