Prognostic value of decreased FOXP1 protein expression in various tumors: a systematic review and meta-analysis

The prognostic value of forkhead box protein P1 (FOXP1) protein expression in tumors remains controversial. Therefore, we conducted a systematic review and meta-analysis, searching the PubMed, Embase and Web of Science databases to identify eligible studies. In total, we analyzed 22 articles that ex...

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Veröffentlicht in:	Scientific reports 2016-07, Vol.6 (1), p.30437-30437, Article 30437
Hauptverfasser:	Xiao, Jian, He, Bixiu, Zou, Yong, Chen, Xi, Lu, Xiaoxiao, Xie, Mingxuan, Li, Wei, He, Shuya, You, Shaojin, Chen, Qiong
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/1857 631/67/395 Disease-Free Survival Forkhead Transcription Factors - metabolism Humanities and Social Sciences Humans multidisciplinary Neoplasm Recurrence, Local - pathology Neoplasms - metabolism Prognosis Publication Bias Repressor Proteins - metabolism Science Science (multidisciplinary)
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Zusammenfassung:	The prognostic value of forkhead box protein P1 (FOXP1) protein expression in tumors remains controversial. Therefore, we conducted a systematic review and meta-analysis, searching the PubMed, Embase and Web of Science databases to identify eligible studies. In total, we analyzed 22 articles that examined 9 tumor types and included 2468 patients. Overall, decreased expression of FOXP1 protein was associated with favorable overall survival (OS) in lymphoma patients (HR = 0.38, 95%CI: 0.30–0.48, p
ISSN:	2045-2322 2045-2322
DOI:	10.1038/srep30437