Targeted radiotherapy enhancement during electronic brachytherapy of accelerated partial breast irradiation (APBI) using controlled release of gold nanoparticles
Highlights • We propose to use gold nanoparticles (GNPs) during APBI to provide dose boost. • We propose delivery of GNPs by coating the Xoft balloon applicator. • We calculate the dose enhancement factor by performing analytical calculations. • Dose enhancement values of 1.2 were found 6 mm away fr...
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| Veröffentlicht in: | Physica medica 2015-12, Vol.31 (8), p.1070-1074 |
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| container_end_page | 1074 |
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| container_issue | 8 |
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| container_title | Physica medica |
| container_volume | 31 |
| creator | Cifter, G Chin, J Cifter, F Altundal, Y Sinha, N Sajo, E Ngwa, W |
| description | Highlights • We propose to use gold nanoparticles (GNPs) during APBI to provide dose boost. • We propose delivery of GNPs by coating the Xoft balloon applicator. • We calculate the dose enhancement factor by performing analytical calculations. • Dose enhancement values of 1.2 were found 6 mm away from lumpectomy cavity surface. |
| doi_str_mv | 10.1016/j.ejmp.2015.07.138 |
| format | Article |
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| fulltext | fulltext |
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| ispartof | Physica medica, 2015-12, Vol.31 (8), p.1070-1074 |
| issn | 1120-1797 1724-191X |
| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | 50 kVp APBI Brachytherapy - instrumentation Breast - drug effects Breast - radiation effects Breast Neoplasms - radiotherapy Delayed-Action Preparations Dose enhancement Electrical Equipment and Supplies Feasibility Studies Gold Gold - administration & dosage Gold - chemistry Gold - pharmacology Humans Metal Nanoparticles Nanoparticles Radiation-Sensitizing Agents - administration & dosage Radiation-Sensitizing Agents - chemistry Radiation-Sensitizing Agents - pharmacology Radiology Radiometry Radiotherapy Dosage Xoft electronic brachytherapy |
| title | Targeted radiotherapy enhancement during electronic brachytherapy of accelerated partial breast irradiation (APBI) using controlled release of gold nanoparticles |
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