Motivational Interviewing Improves Medication Adherence: a Systematic Review and Meta-analysis

Background Randomized clinical trials (RCTs), mostly conducted among minority populations, have reported that motivational interviewing (MI) can improve medication adherence. Objectives To evaluate the impact of MI and of the MI delivery format, fidelity assessment, fidelity-based feedback, counselo...

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Veröffentlicht in:Journal of general internal medicine : JGIM 2016-08, Vol.31 (8), p.929-940
Hauptverfasser: Palacio, Ana, Garay, Desiree, Langer, Benjamin, Taylor, Janielle, Wood, Barbara A., Tamariz, Leonardo
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Sprache:eng
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Zusammenfassung:Background Randomized clinical trials (RCTs), mostly conducted among minority populations, have reported that motivational interviewing (MI) can improve medication adherence. Objectives To evaluate the impact of MI and of the MI delivery format, fidelity assessment, fidelity-based feedback, counselors’ background and MI exposure time on adherence. Data Sources We searched the MEDLINE database for studies published from 1966 until February 2015. Study Eligibility Criteria We included RCTs that compared MI to a control group and reported a numerical measure of medication adherence. Data Synthesis The main outcome was medication adherence defined as any subjective or objective measure reported as the proportion of subjects with adequate adherence or mean adherence and standard deviation. For categorical variables we calculated the relative risk (RR) of medication adherence, and for continuous variables we calculated the standardized mean difference (SMD) between the MI and control groups. Results We included 17 RCTs. Ten targeted adherence to HAART. For studies reporting a categorical measure (n = 11), the pooled RR for medication adherence was higher for MI compared with control (1.17; 95 % CI 1.05- 1.31; p 
ISSN:0884-8734
1525-1497
DOI:10.1007/s11606-016-3685-3