Factors Associated with the Success of In Vitro Fertilization in Women with Inflammatory Bowel Disease

Background It is unknown whether certain factors are associated with the success of in vitro fertilization (IVF) in women with inflammatory bowel disease (IBD). Aim This study assessed whether certain characteristics are associated with greater success of live birth following IVF. Methods In a cohort study of 8684 women with IBD seen at two tertiary care centers, we identified 121 women with IBD who underwent IVF. We assessed the effect of numerous factors on likelihood of achieving live birth after IVF. Results Seventy-one patients with ulcerative colitis (UC) and 49 patients with Crohn’s disease (CD) were analyzed. Patients with UC who achieved a live birth were younger ( p = 0.03), had a shorter duration of disease ( p = 0.01), and were more likely to be in remission ( p = 0.03) versus those who did not achieve live birth. Patients with CD who achieved live birth were younger ( p