Predictors of response to pegylated interferon in chronic hepatitis B: a real-world hospital-based analysis

Predictors of response to pegylated interferon in chronic hepatitis B: a real-world hospital-based analysis

Information on the efficacy of pegylated interferon (PEG-IFN) treatment of chronic hepatitis B (CHB) patients and predictors of the response based on real-world data is limited. Consecutive 201 patients who underwent PEG-IFN treatment for CHB were reviewed. A virological response (VR) was defined as...

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Veröffentlicht in:Scientific reports 2016-07, Vol.6 (1), p.29605-29605, Article 29605
Hauptverfasser: Wang, Yin-Chen, Yang, Sien-Sing, Su, Chien-Wei, Wang, Yuan-Jen, Lee, Kuei-Chuan, Huo, Teh-Ia, Lin, Han-Chieh, Huang, Yi-Hsiang
Format: Artikel
Sprache:eng
Schlagworte:
692/4020/4021/1607/234/2513/1549
692/4020/4021/234/2513/1549
Clinical medicine
Drug resistance
Hepatitis B
Hospitals
Humanities and Social Sciences
Infections
Interferon
Liver cancer
Liver cirrhosis
Medicine
multidisciplinary
Patients
Regression analysis
Review boards
Science
Science (multidisciplinary)
Serology
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Zusammenfassung:Information on the efficacy of pegylated interferon (PEG-IFN) treatment of chronic hepatitis B (CHB) patients and predictors of the response based on real-world data is limited. Consecutive 201 patients who underwent PEG-IFN treatment for CHB were reviewed. A virological response (VR) was defined as a serum HBV DNA of
ISSN:2045-2322
2045-2322
DOI:10.1038/srep29605