Tunable, biodegradable gold nanoparticles as contrast agents for computed tomography and photoacoustic imaging

Abstract Gold nanoparticles (AuNP) have been proposed for many applications in medicine. Although large AuNP (>5.5 nm) are desirable for their longer blood circulation and accumulation in diseased tissues, small AuNP (

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Bibliographische Detailangaben
Veröffentlicht in:	Biomaterials 2016-09, Vol.102, p.87-97
Hauptverfasser:	Cheheltani, Rabee, Ezzibdeh, Rami M, Chhour, Peter, Pulaparthi, Kumidini, Kim, Johoon, Jurcova, Martina, Hsu, Jessica C, Blundell, Cassidy, Litt, Harold I, Ferrari, Victor A, Allcock, Harry R, Sehgal, Chandra M, Cormode, David P
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Animals Biocompatibility Biodegradability blood circulation byproducts Cell Line composite polymers Computed tomography Contrast agent Contrast agents Contrast Media - chemistry Dentistry encapsulation Excretion Gold Gold - chemistry Gold nanoparticle Humans image analysis Imaging In vitro testing in vivo studies kidneys medicine Metal Nanoparticles - chemistry Metal Nanoparticles - ultrastructure Metal-polymer nanoparticle Mice, Inbred C57BL nanogold Nanoparticles nanospheres Organophosphorus Compounds - chemistry Photoacoustic imaging Photoacoustic Techniques - methods polyethylene Polymers - chemistry tissues Tomography, X-Ray Computed - methods transmission electron microscopy ultraviolet-visible spectroscopy
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Beschreibung
Zusammenfassung:	Abstract Gold nanoparticles (AuNP) have been proposed for many applications in medicine. Although large AuNP (>5.5 nm) are desirable for their longer blood circulation and accumulation in diseased tissues, small AuNP (
ISSN:	0142-9612 1878-5905
DOI:	10.1016/j.biomaterials.2016.06.015