General intelligence is associated with subclinical inflammation in Nepalese children: a population-based plasma proteomics study

Highlights • Proteomics was applied to identify plasma proteins associated with child cognition. • Nutrition sensitive proteins were associated with increased intelligence test scores. • Inflammatory proteins were associated with low scores, independent of risk factors. • A protein regulating glycol...

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Veröffentlicht in:Brain, behavior, and immunity behavior, and immunity, 2016-08, Vol.56, p.253-263
Hauptverfasser: Lee, Sun Eun, West, Keith P, Cole, Robert N, Schulze, Kerry J, Wu, Lee Shu-Fune, Yager, James D, Groopman, John, Christian, Parul
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Sprache:eng
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Zusammenfassung:Highlights • Proteomics was applied to identify plasma proteins associated with child cognition. • Nutrition sensitive proteins were associated with increased intelligence test scores. • Inflammatory proteins were associated with low scores, independent of risk factors. • A protein regulating glycolysis contributed to the variability in the test scores. • Plasma proteomics can provide candidate proteins associated with child cognition.
ISSN:0889-1591
1090-2139
DOI:10.1016/j.bbi.2016.03.023