Habitual physical activity is associated with the maintenance of neutrophil migratory dynamics in healthy older adults

Highlights • Higher habitual physical activity in over 65 year olds is associated with the maintenance of neutrophil migratory dynamics towards IL-8. • The effect occurs independently of systemic inflammation or surface chemokine receptor expression. • Adiponectin levels may positively influence neu...

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Veröffentlicht in:	Brain, behavior, and immunity behavior, and immunity, 2016-08, Vol.56, p.12-20
Hauptverfasser:	Bartlett, David B, Fox, Oliver, McNulty, Clare L, Greenwood, Hannah L, Murphy, Laura, Sapey, Elizabeth, Goodman, Martin, Crabtree, Nicola, Thøgersen-Ntoumani, Cecilie, Fisher, James P, Wagenmakers, Anton J.M, Lord, Janet M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Ageing Aging - blood Aging - immunology Aging - physiology Allergy and Immunology Cell Movement - physiology Escherichia coli Exercise - physiology Female Full-length Humans Immunity, Innate - physiology Immunosenescence Immunosenescence - immunology Inflammation Innate immunity Male Migration Neutrophil Neutrophils - physiology Physical activity Psychiatry
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Zusammenfassung:	Highlights • Higher habitual physical activity in over 65 year olds is associated with the maintenance of neutrophil migratory dynamics towards IL-8. • The effect occurs independently of systemic inflammation or surface chemokine receptor expression. • Adiponectin levels may positively influence neutrophil migration.
ISSN:	0889-1591 1090-2139
DOI:	10.1016/j.bbi.2016.02.024