Potential Use of Fosfomycin-Tromethamine for Treatment of Recurrent Campylobacter Species Enteritis

We report 2 cases of recurrent Campylobacter coli enteritis caused by macrolide- and fluoroquinolone-resistant strains in 2 patients with hypogammaglobulinemia, successfully treated with a prolonged course of fosfomycin-tromethamine with no side effects. Fosfomycin-tromethamine may be a feasible alt...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2016-07, Vol.60 (7), p.4398-4400
Hauptverfasser:	Aguilar-Company, Juan, Los-Arcos, Ibai, Pigrau, Carles, Rodríguez-Pardo, Dolors, Larrosa, María Nieves, Rodríguez-Garrido, Virginia, Sihuay-Diburga, Denisse, Almirante, Benito
Format:	Artikel
Sprache:	eng
Schlagworte:	Agammaglobulinemia - drug therapy Aged, 80 and over Anti-Bacterial Agents Anti-Bacterial Agents - therapeutic use Campylobacter Campylobacter - drug effects Campylobacter - pathogenicity Campylobacter coli Clinical Therapeutics Enteritis Enteritis - drug therapy Female Fosfomycin Fosfomycin - therapeutic use Humans Microbial Sensitivity Tests Middle Aged Tromethamine Tromethamine - therapeutic use
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Zusammenfassung:	We report 2 cases of recurrent Campylobacter coli enteritis caused by macrolide- and fluoroquinolone-resistant strains in 2 patients with hypogammaglobulinemia, successfully treated with a prolonged course of fosfomycin-tromethamine with no side effects. Fosfomycin-tromethamine may be a feasible alternative therapy for recurrent enteritis caused by Campylobacter species resistant to first-line drugs.
ISSN:	0066-4804 1098-6596
DOI:	10.1128/AAC.00447-16