Impact of enterovirus and other enteric pathogens on oral polio and rotavirus vaccine performance in Bangladeshi infants

Highlights • Oral vaccines exhibit poor performance in low-income settings. • Enterovirus and Campylobacter carriage are associated with lower OPV immunogenicity. • Enterovirus carriage is associated with lower Rotarix immunogenicity and efficacy.

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Bibliographische Detailangaben
Veröffentlicht in:	Vaccine 2016-06, Vol.34 (27), p.3068-3075
Hauptverfasser:	Taniuchi, Mami, Platts-Mills, James A, Begum, Sharmin, Uddin, Md Jashim, Sobuz, Shihab U, Liu, Jie, Kirkpatrick, Beth D, Colgate, E. Ross, Carmolli, Marya P, Dickson, Dorothy M, Nayak, Uma, Haque, Rashidul, Petri, William A, Houpt, Eric R
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Allergy and Immunology Antibodies, Neutralizing - blood Antibodies, Viral - blood Bangladesh Campylobacter Campylobacter Infections - immunology Child, Preschool Deoxyribonucleic acid Diarrhea DNA Enteric infections Enterovirus Enterovirus Infections - immunology Feces Female Humans Immunization Immunogenicity Immunoglobulin A - blood Infant Infants Infections Low income groups Male Oral polio vaccine Parasites PCR Picornaviridae Poliomyelitis Poliovirus Vaccine, Oral - therapeutic use Regression analysis Reoviridae Rotavirus Rotavirus vaccine Rotavirus Vaccines - therapeutic use Shipments Studies Vaccine efficacy Vaccine immunogenicity Vaccines Vaccines, Attenuated - therapeutic use Viruses
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Beschreibung
Zusammenfassung:	Highlights • Oral vaccines exhibit poor performance in low-income settings. • Enterovirus and Campylobacter carriage are associated with lower OPV immunogenicity. • Enterovirus carriage is associated with lower Rotarix immunogenicity and efficacy.
ISSN:	0264-410X 1873-2518
DOI:	10.1016/j.vaccine.2016.04.080