Dominant eye and visual evoked potential of patients with myopic anisometropia

A prospective nonrandomized controlled study was conducted to explore the association between ocular dominance and degree of myopia in patients with anisometropia and to investigate the character of visual evoked potential (VEP) in high anisometropias. 1771 young myopia cases including 790 anisometropias were recruited. We found no significant relation between ocular dominance and spherical equivalent (SE) refraction in all subjects. On average for subjects with anisometropia 1.0–1.75 D, there was no significant difference in SE power between dominant and nondominant eyes, while, in SE anisometropia ≥1.75 D group, the degree of myopia was significantly higher in nondominant eyes than in dominant eyes. The trend was more significant in SE anisometropia ≥2.5 D group. There was no significant difference in higher-order aberrations between dominant eye and nondominant eye either in the whole study candidates or in any anisometropia groups. In anisometropias >2.0 D, the N75 latency of nondominant eye was longer than that of dominant eye. Our results suggested that, with the increase of anisometropia, nondominant eye had a tendency of higher refraction and N75 wave latency of nondominant eye was longer than that of dominant eye in high anisometropias.