Effects of estrogen on cerebrovascular function: age-dependent shifts from beneficial to detrimental in small cerebral arteries of the rat

In the present study, interactions of age and estrogen in the modulation of cerebrovascular function were examined in small arteries

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Bibliographische Detailangaben
Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2016-05, Vol.310 (10), p.H1285-H1294
Hauptverfasser:	Deer, Rachel R, Stallone, John N
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Animals Call for Papers Dose-Response Relationship, Drug Epoprostenol - metabolism Estradiol - administration & dosage Estradiol - toxicity Estrogen Replacement Therapy - adverse effects Estrogens Hormone replacement therapy Middle Cerebral Artery - drug effects Middle Cerebral Artery - metabolism Ovariectomy Rats, Sprague-Dawley Rodents Signal Transduction - drug effects Thromboxane A2 - metabolism Vasoconstriction - drug effects Vasoconstrictor Agents - pharmacology Vasopressins - pharmacology Veins & arteries
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Beschreibung
Zusammenfassung:	In the present study, interactions of age and estrogen in the modulation of cerebrovascular function were examined in small arteries
ISSN:	0363-6135 1522-1539
DOI:	10.1152/ajpheart.00645.2015