Vascular Response to Experimental Stent Malapposition and Under-Expansion

Vascular Response to Experimental Stent Malapposition and Under-Expansion

Up to 80% of all endovascular stents have malapposed struts, and while some impose catastrophic events others are inconsequential. Thirteen stents were implanted in coronary arteries of seven healthy Yorkshire pigs, using specially-designed cuffed balloons inducing controlled stent malapposition and...

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Veröffentlicht in:Annals of biomedical engineering 2016-07, Vol.44 (7), p.2251-2260
Hauptverfasser: O’Brien, Caroline C., Lopes, Augusto C., Kolandaivelu, Kumaran, Kunio, Mie, Brown, Jonathan, Kolachalama, Vijaya B., Conway, Claire, Bailey, Lynn, Markham, Peter, Costa, Marco, Ware, James, Edelman, Elazer R.
Format: Artikel
Sprache:eng
Schlagworte:
Animal models
Animals
Arteries
Biochemistry
Biological and Medical Physics
Biomedical and Life Sciences
Biomedical Engineering and Bioengineering
Biomedicine
Biophysics
Classical Mechanics
Coronary Vessels - diagnostic imaging
Coronary Vessels - physiopathology
Correlation
Elasticity
Imaging
Laminates
Lumens
Medical equipment
Models, Cardiovascular
Percutaneous Coronary Intervention - adverse effects
Stents - adverse effects
Struts
Surgical implants
Swine
Tomography, Optical Coherence
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Beschreibung
Zusammenfassung:Up to 80% of all endovascular stents have malapposed struts, and while some impose catastrophic events others are inconsequential. Thirteen stents were implanted in coronary arteries of seven healthy Yorkshire pigs, using specially-designed cuffed balloons inducing controlled stent malapposition and under-expansion. Optical coherence tomography (OCT) imaging confirmed that 25% of struts were malapposed (strut-wall distance
ISSN:0090-6964
1573-9686
DOI:10.1007/s10439-015-1518-x