Breastmilk from obese mothers has pro-inflammatory properties and decreased neuroprotective factors

Objective: To determine the impact of maternal obesity on breastmilk composition. Study Design: Breastmilk and food records from 21 lean and 21 obese women who delivered full-term infants were analyzed at 2 months post-partum. Infant growth and adiposity were measured at birth and 2 months of age. R...

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Veröffentlicht in:	Journal of perinatology 2016-04, Vol.36 (4), p.284-290
Hauptverfasser:	Panagos, P G, Vishwanathan, R, Penfield-Cyr, A, Matthan, N R, Shivappa, N, Wirth, M D, Hebert, J R, Sen, S
Format:	Artikel
Sprache:	eng
Schlagworte:	692/308/575 692/420/256/2515 Adipose tissue Analysis Body mass Body Mass Index Body size Breast milk Carotenoids Case-Control Studies Child Development Diet Docosahexaenoic acid Eicosapentaenoic acid Fatty acids Fatty Acids - analysis Female Health aspects Humans Infant Infant, Newborn Infants Inflammation Lutein Lutein - analysis Medicine Medicine & Public Health Milk, Human - chemistry Milk, Human - immunology Mothers Neurodevelopment Neuroprotection Obesity Obesity - physiopathology Omega-3 fatty acids original-article Pediatric Surgery Pediatrics Physical growth Physiological aspects Pregnancy
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Zusammenfassung:	Objective: To determine the impact of maternal obesity on breastmilk composition. Study Design: Breastmilk and food records from 21 lean and 21 obese women who delivered full-term infants were analyzed at 2 months post-partum. Infant growth and adiposity were measured at birth and 2 months of age. Result: Breastmilk from obese mothers had higher omega-6 to omega-3 fatty acid ratio and lower concentrations of docosahexaenoic acid, eicosapentaenoic acid, docasapentaenoic acid and lutein compared with lean mothers ( P
ISSN:	0743-8346 1476-5543
DOI:	10.1038/jp.2015.199