Levels of albuminuria and risk of developing macroalbuminuria in type 2 diabetes: historical cohort study

Although increased urinary albumin excretion may increase the risk of adverse renal outcomes in patients with diabetes, it remains unclear whether microalbuminuria is associated with a higher incidence of macroalbuminuria in the absence of non-diabetic kidney events that frequently develop during th...

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Veröffentlicht in:	Scientific reports 2016-05, Vol.6 (1), p.26380-26380, Article 26380
Hauptverfasser:	Chida, Shoma, Fujita, Yoshikuni, Ogawa, Akifumi, Hayashi, Akinori, Ichikawa, Raishi, Kamata, Yuji, Takeuchi, Akihiro, Takano, Koji, Shichiri, Masayoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	692/163/2743/137/138 692/4022/1585/104 Aged Albumin Albuminuria - diagnosis Albuminuria - epidemiology Cohort analysis Cohort Studies Creatinine Creatinine - blood Diabetes Diabetes mellitus Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - urine Disease Progression Excretion Female Health risk assessment Humanities and Social Sciences Humans Incidence Kidney transplantation Kidneys Male Middle Aged multidisciplinary Nephropathy ROC Curve Science Science (multidisciplinary) Serum Albumin, Human - urine Urine
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Zusammenfassung:	Although increased urinary albumin excretion may increase the risk of adverse renal outcomes in patients with diabetes, it remains unclear whether microalbuminuria is associated with a higher incidence of macroalbuminuria in the absence of non-diabetic kidney events that frequently develop during the long-term course of type 2 diabetes. This historical cohort study included patients with type 2 diabetes, spot urine albumin:creatinine ratio (ACR)
ISSN:	2045-2322 2045-2322
DOI:	10.1038/srep26380