Clinical Outcomes and Prognostic Factors for Salivary Duct Carcinoma: A Multi-Institutional Analysis of 141 Patients

Background Among salivary gland malignancies, the prognosis of salivary duct carcinoma (SDC) is assumed to be the poorest. However, because of its low incidence, reliable survival estimates and prognostic factors based on a large number of patients remain to be elucidated, thereby making it impossib...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Annals of surgical oncology 2016-06, Vol.23 (6), p.2038-2045
Hauptverfasser:	Otsuka, Kuninori, Imanishi, Yorihisa, Tada, Yuichiro, Kawakita, Daisuke, Kano, Satoshi, Tsukahara, Kiyoaki, Shimizu, Akira, Ozawa, Hiroyuki, Okami, Kenji, Sakai, Akihiro, Sato, Yuichiro, Ueki, Yushi, Sato, Yukiko, Hanazawa, Toyoyuki, Chazono, Hideaki, Ogawa, Kaoru, Nagao, Toshitaka
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Carcinoma, Ductal - pathology Carcinoma, Ductal - surgery Clinical outcomes Female Follow-Up Studies Head and Neck Oncology Humans Male Medicine Medicine & Public Health Middle Aged Oncology Prognosis Retrospective Studies Salivary Gland Neoplasms - pathology Salivary Gland Neoplasms - surgery Surgery Surgical Oncology Survival Rate
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Background Among salivary gland malignancies, the prognosis of salivary duct carcinoma (SDC) is assumed to be the poorest. However, because of its low incidence, reliable survival estimates and prognostic factors based on a large number of patients remain to be elucidated, thereby making it impossible to standardize the optimal treatment for SDC. Methods We performed this multi-institutional, retrospective analysis by collecting the clinical information of 141 patients with SDC without distant metastasis who underwent curative surgery as the initial treatment to elucidate overall survival (OS) and disease-free survival (DFS) along with their prognostic factors. Results The 3-year OS and DFS rates were 70.5 and 38.2 %, respectively. Multivariate analysis revealed that age ≥65 years ( p
ISSN:	1068-9265 1534-4681
DOI:	10.1245/s10434-015-5082-2