Physicochemical Approach to Determine the Mechanism for Acid–Base Disorders in 793 Hospitalized Foals

Physicochemical Approach to Determine the Mechanism for Acid–Base Disorders in 793 Hospitalized Foals

BACKGROUND: The quantitative effect of strong electrolytes, unmeasured strong anions (UAs), pCO₂, and plasma protein concentrations in determining plasma pH can be demonstrated using the physicochemical approach. Plasma anion gap (AG) and strong ion gap (SIG) are used to assess UAs in different spec...

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Veröffentlicht in:Journal of veterinary internal medicine 2015-09, Vol.29 (5), p.1395-1402
Hauptverfasser: Gomez, D.E., Biermann, N.M., Sanchez, L.C.
Format: Artikel
Sprache:eng
Schlagworte:
Acid-Base Equilibrium
Acid-Base Imbalance - blood
Acid-Base Imbalance - diagnosis
Acid-Base Imbalance - veterinary
Animals
Animals, Newborn - blood
Anion gap
Chlorides - blood
EQUID
Female
Horse Diseases - blood
Horse Diseases - diagnosis
Horses
Hydrogen-Ion Concentration
Lactates - blood
Male
Nonvolatile weak acids
Potassium - blood
Retrospective Studies
Sodium - blood
Strong ion difference
Strong ion gap
Unmeasured anions
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Zusammenfassung:BACKGROUND: The quantitative effect of strong electrolytes, unmeasured strong anions (UAs), pCO₂, and plasma protein concentrations in determining plasma pH can be demonstrated using the physicochemical approach. Plasma anion gap (AG) and strong ion gap (SIG) are used to assess UAs in different species. HYPOTHESES: Strong ions are a major factor influencing changes in plasma pH of hospitalized foals. AG and SIG accurately predict severe hyper‐l‐lactatemia ([l‐lac⁻] > 7 mmol/L). ANIMALS: Seven hundred and ninety three hospitalized foals 
ISSN:0891-6640
1939-1676
DOI:10.1111/jvim.13590