Expression and localization of Inter-alpha Inhibitors in rodent brain

Highlights • Proteins and mRNA of IAIP light and heavy chains are expressed in mouse neurons. • Proteins of IAIPs were detected in cultured rat neurons, microglia, and astrocytes. • IAIP immunoreactivity was detected in different brain regions. • IAIPs are expressed in a wide variety of brain cells...

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Veröffentlicht in:	Neuroscience 2016-06, Vol.324, p.69-81
Hauptverfasser:	Chen, X, Rivard, L, Naqvi, S, Nakada, S, Padbury, J.F, Sanchez-Esteban, J, Stopa, E.G, Lim, Y.-P, Stonestreet, B.S
Format:	Artikel
Sprache:	eng
Schlagworte:	Alpha-Globulins - metabolism Animals Astrocytes - cytology Astrocytes - metabolism Brain - cytology Brain - growth & development Brain - metabolism cell culture Cells, Cultured fetal Immunohistochemistry Inter-alpha Inhibitors Mice, Inbred C57BL Microglia - cytology Microglia - metabolism neonate Neurology neurons Neurons - cytology Neurons - metabolism Rats, Wistar RNA, Messenger - metabolism rodent
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Beschreibung
Zusammenfassung:	Highlights • Proteins and mRNA of IAIP light and heavy chains are expressed in mouse neurons. • Proteins of IAIPs were detected in cultured rat neurons, microglia, and astrocytes. • IAIP immunoreactivity was detected in different brain regions. • IAIPs are expressed in a wide variety of brain cells and regions in rodent CNS.
ISSN:	0306-4522 1873-7544
DOI:	10.1016/j.neuroscience.2016.03.009