Squamous cell carcinoma of the oral cavity often overexpresses p16 but is rarely driven by human papillomavirus

Highlights • Very few patients with oral cavity cancer have HPV-driven tumors. • HPV status is not correlated with survival outcomes of oral cavity cancer. • p16 does not clinically correlate with HPV positivity in oral cavity cancer.

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Veröffentlicht in:Oral oncology 2016-05, Vol.56, p.47-53
Hauptverfasser: Zafereo, Mark E, Xu, Li, Dahlstrom, Kristina R, Viamonte, Carlo A, El-Naggar, Adel K, Wei, Qingyi, Li, Guojun, Sturgis, Erich M
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Sprache:eng
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Zusammenfassung:Highlights • Very few patients with oral cavity cancer have HPV-driven tumors. • HPV status is not correlated with survival outcomes of oral cavity cancer. • p16 does not clinically correlate with HPV positivity in oral cavity cancer.
ISSN:1368-8375
1879-0593
DOI:10.1016/j.oraloncology.2016.03.003