Nuclear factor-κB regulates the expression of multiple genes encoding liver transport proteins

In this study we identified the mechanisms underlying the inhibitory effects of NF-κB on the expression of genes encoding multiple liver transport proteins. Well-conserved NF-κB binding sites were found in the promoters of farnesoid X receptor (FXR)-target genes. An electromobility shift assay (EMSA...

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Veröffentlicht in:American journal of physiology: Gastrointestinal and liver physiology 2016-04, Vol.310 (8), p.G618-G628
Hauptverfasser: Balasubramaniyan, Natarajan, Ananthanarayanan, Meenakshisundaram, Suchy, Frederick J
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Sprache:eng
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