Effect of Light Scattering and Higher-order Aberrations on Visual Performance in Eyes with Granular Corneal Dystrophy

This study was aimed to assess the relationship of intraocular forward scattering, corneal backward scattering and corneal higher-order aberrations (HOAs) with corrected distance visual acuity (CDVA) in eyes with granular corneal dystrophy (GCD). We retrospectively examined forty two eyes of 42 consecutive patients who diagnosed GCD and age-matched 20 eyes of 20 healthy subjects. We assessed objective scattering index (OSI) using the double-pass instrument (OQAS II, Visiometrics), corneal densitometry (CD) using the Scheimpflug rotating camera (Pentacam HR, Oculus) and corneal HOAs using the Hartmann-Shack aberrometry (KR-9000, Topcon). The OSI, CD and corneal HOAs were significantly larger in the GCD group than those in the control group (Mann-Whitney U test, p