Neurobehavioral development of common marmoset monkeys

ABSTRACT Common marmoset (Callithrix jacchus) monkeys are a resource for biomedical research and their use is predicted to increase due to the suitability of this species for transgenic approaches. Identification of abnormal neurodevelopment due to genetic modification relies upon the comparison wit...

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Veröffentlicht in:Developmental psychobiology 2016-03, Vol.58 (2), p.141-158
Hauptverfasser: Schultz-Darken, Nancy, Braun, Katarina M., Emborg, Marina E.
Format: Artikel
Sprache:eng
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Zusammenfassung:ABSTRACT Common marmoset (Callithrix jacchus) monkeys are a resource for biomedical research and their use is predicted to increase due to the suitability of this species for transgenic approaches. Identification of abnormal neurodevelopment due to genetic modification relies upon the comparison with validated patterns of normal behavior defined by unbiased methods. As scientists unfamiliar with nonhuman primate development are interested to apply genomic editing techniques in marmosets, it would be beneficial to the field that the investigators use validated methods of postnatal evaluation that are age and species appropriate. This review aims to analyze current available data on marmoset physical and behavioral postnatal development, describe the methods used and discuss next steps to better understand and evaluate marmoset normal and abnormal postnatal neurodevelopment. © 2015 Wiley Periodicals, Inc. Dev Psychobiol 58: 141–158, 2016.
ISSN:0012-1630
1098-2302
DOI:10.1002/dev.21360