Glasgow prognostic score predicts prognosis of non-small cell lung cancer: a meta-analysis

Glasgow prognostic score predicts prognosis of non-small cell lung cancer: a meta-analysis

Objective Glasgow prognostic score (GPS), an inflammation-based scoring system, has been evaluated in various cancers. However, its clinical significance remains unclear in non-small cell lung cancer (NSCLC). Therefore, it is necessary to conduct a meta-analysis to explore the prognostic value of GP...

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Veröffentlicht in:SpringerPlus 2016-04, Vol.5 (1), p.439-439, Article 439
Hauptverfasser: Zhu, Lucheng, Chen, Sumei, Ma, Shenglin, Zhang, Shirong
Format: Artikel
Sprache:eng
Schlagworte:
Biomedical and Life Sciences
Humanities and Social Sciences
Lung cancer
multidisciplinary
Science
Science (multidisciplinary)
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Zusammenfassung:Objective Glasgow prognostic score (GPS), an inflammation-based scoring system, has been evaluated in various cancers. However, its clinical significance remains unclear in non-small cell lung cancer (NSCLC). Therefore, it is necessary to conduct a meta-analysis to explore the prognostic value of GPS in NSCLC patients. Methods A quantitative meta-analysis was performed through a systematic search in PubMed, Web of Science, and the Cochrane Library. The pooled hazard ratios (HRs) of overall survival (OS) were calculated and compared. Results A total of 12 studies comprising 2669 patients were included in this meta-analysis. Compared with GPS 0 group, patients in GPS 1–2 group exhibited a reduced OS with a pooled HR of 1.89 (95 % CI 1.57–2.27, p  
ISSN:2193-1801
2193-1801
DOI:10.1186/s40064-016-2093-9