Gastric bypass surgery vs intensive lifestyle and medical intervention for type 2 diabetes: the CROSSROADS randomised controlled trial

Aims/hypothesis Mounting evidence indicates that Roux-en-Y gastric bypass (RYGB) ameliorates type 2 diabetes, but randomised trials comparing surgical vs nonsurgical care are needed. With a parallel-group randomised controlled trial (RCT), we compared RYGB vs an intensive lifestyle and medical inter...

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Veröffentlicht in:	Diabetologia 2016-05, Vol.59 (5), p.945-953
Hauptverfasser:	Cummings, David E., Arterburn, David E., Westbrook, Emily O., Kuzma, Jessica N., Stewart, Skye D., Chan, Chun P., Bock, Steven N., Landers, Jeffrey T., Kratz, Mario, Foster-Schubert, Karen E., Flum, David R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - surgery Diabetes Mellitus, Type 2 - therapy Female Gastric Bypass Gastrointestinal surgery Healthy Lifestyle Human Physiology Humans Hypoglycemic Agents - therapeutic use Internal Medicine Male Medical research Medicine Medicine & Public Health Metabolic Diseases Middle Aged Obesity Remission (Medicine) Treatment Outcome
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Zusammenfassung:	Aims/hypothesis Mounting evidence indicates that Roux-en-Y gastric bypass (RYGB) ameliorates type 2 diabetes, but randomised trials comparing surgical vs nonsurgical care are needed. With a parallel-group randomised controlled trial (RCT), we compared RYGB vs an intensive lifestyle and medical intervention (ILMI) for type 2 diabetes, including among patients with a BMI
ISSN:	0012-186X 1432-0428
DOI:	10.1007/s00125-016-3903-x