Pre-diagnosis blood glucose and prognosis in women with breast cancer

The effect of moderately elevated blood glucose levels among non-diabetic subjects on cancer prognosis is not well described. The goal of this study was to examine the association of elevated random blood glucose (RBG) levels in non-diabetic breast cancer patients with overall survival (OS) and time...

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Veröffentlicht in:Cancer & metabolism 2016-04, Vol.4 (6), p.7-7, Article 7
Hauptverfasser: Monzavi-Karbassi, Behjatolah, Gentry, Rhonda, Kaur, Varinder, Siegel, Eric R, Jousheghany, Fariba, Medarametla, Srikanth, Fuhrman, Barbara J, Safar, A Mazin, Hutchins, Laura F, Kieber-Emmons, Thomas
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Sprache:eng
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Zusammenfassung:The effect of moderately elevated blood glucose levels among non-diabetic subjects on cancer prognosis is not well described. The goal of this study was to examine the association of elevated random blood glucose (RBG) levels in non-diabetic breast cancer patients with overall survival (OS) and time to tumor recurrence (TTR). Forty-nine deaths and 32 recurrences occurred among 148 eligible study subjects during 855.44 person-years of follow-up, with median follow-up of 5.97 years. We observed that patients with elevated RBG levels experienced significantly shorter OS (hazard ratio [HR], 3.01; 95 % confidence interval [CI] (1.70-5.33); P 
ISSN:2049-3002
2049-3002
DOI:10.1186/s40170-016-0147-7