Prognostic Value of Galectin-3 for Adverse Outcomes in Chronic Heart Failure

Prognostic Value of Galectin-3 for Adverse Outcomes in Chronic Heart Failure

Highlights • Age, symptoms of heart failure, and renal function affected galectin-3 levels. • Galectin-3 was strongly associated with adverse terminal outcomes in heart failure. • Compared with established biomarkers, galectin-3 discriminated risk less accurately. • Among patients with preserved eje...

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Veröffentlicht in:Journal of cardiac failure 2016-04, Vol.22 (4), p.256-262
Hauptverfasser: French, Benjamin, PhD, Wang, Le, MS, Ky, Bonnie, MD, MSCE, Brandimarto, Jeffrey, MS, Basuray, Anupam, MD, MPH, Fang, James C., MD, Sweitzer, Nancy K., MD, PhD, Cappola, Thomas P., MD, ScM
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Biomarker
Biomarkers - blood
Cardiovascular
Chronic Disease
Cohort Studies
ejection fraction
Female
Follow-Up Studies
Galectin 3 - blood
Heart Failure - blood
Heart Failure - diagnosis
Heart Failure - mortality
Humans
Male
Middle Aged
Mortality - trends
Prognosis
Prospective Studies
risk stratification
Stroke Volume - physiology
Treatment Outcome
ventricular function
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Zusammenfassung:Highlights • Age, symptoms of heart failure, and renal function affected galectin-3 levels. • Galectin-3 was strongly associated with adverse terminal outcomes in heart failure. • Compared with established biomarkers, galectin-3 discriminated risk less accurately. • Among patients with preserved ejection fraction, galectin-3 had high accuracy.
ISSN:1071-9164
1532-8414
DOI:10.1016/j.cardfail.2015.10.022