Profiling cancer metabolism at the 'omic' level: a last resort or the next frontier?

Profiling cancer metabolism at the 'omic' level: a last resort or the next frontier?

A convincing example of the power of untargeted metabolomics to identify serum markers of non-small-cell lung cancer was recently published in the Journal of Clinical Oncology. Untargeted metabolomics provides data on a larger number of compounds, but the data are less quantitatively reliable. [...]...

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Veröffentlicht in:Cancer & metabolism 2016-03, Vol.4 (1), p.2-2, Article 2
Hauptverfasser: Gelman, Susan J, Patti, Gary J
Format: Artikel
Sprache:eng
Schlagworte:
Cancer
Carcinogenesis
Cell metabolism
Data processing
Experiments
Gene expression
Genetic aspects
Genotype
Health aspects
Laboratories
Mass spectrometry
Mathematical models
Metabolism
Metabolites
Properties
Scientific imaging
Studies
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Zusammenfassung:A convincing example of the power of untargeted metabolomics to identify serum markers of non-small-cell lung cancer was recently published in the Journal of Clinical Oncology. Untargeted metabolomics provides data on a larger number of compounds, but the data are less quantitatively reliable. [...]if an investigator has a research question that can be answered with a targeted analysis, that is the recommended experiment.
ISSN:2049-3002
2049-3002
DOI:10.1186/s40170-016-0144-x