Susceptibility weighted imaging: An important tool for early diagnosis of tacrolimus toxicity

Magnetic resonance imaging (MRI) of the brain revealed few small patches of altered signal on the T1- [Figure 1]a and b] and T2-weighted images [Figure 1]c and d in bilateral parietal and frontal lobes, few of the lesions showing restricted diffusion on apparent diffusion coefficient maps [Figure 1]e and f. A diagnosis of recurrent cerebral ischemia with few acute infarcts was made, and the patient managed as such.