During Infection, Theiler's Virions Are Cleaved by Caspases and Disassembled into Pentamers

Infected macrophages in spinal cords of mice persistently infected with Theiler's murine encephalomyelitis virus (TMEV) undergo apoptosis, resulting in restricted virus yields, as do infected macrophages in culture. Apoptosis of murine macrophages in culture occurs via the intrinsic pathway lat...

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Veröffentlicht in:	Journal of virology 2016-04, Vol.90 (7), p.3573-3583
Hauptverfasser:	Arslan, Sevim Yildiz, Son, Kyung-No, Lipton, Howard L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Caspases - metabolism Cells, Cultured Cellular Response to Infection Cricetinae Macrophages - virology Mice Proteolysis Theilovirus - physiology Viral Load Virion - metabolism Virus Assembly
Online-Zugang:	Volltext
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