Hyperactivated mTOR and JAK2/STAT3 Pathways: Molecular Drivers and Potential Therapeutic Targets of Inflammatory and Invasive Ductal Breast Cancers After Neoadjuvant Chemotherapy

Micro-Abstract: Activation of the phosphatidylinositide-3-kinase/mammalian target of rapamycin and Janus kinase/signal transducer and activator of transcription pathways are described in inflammatory breast cancer (IBC) preclinical data. This retrospective analysis of IBC and invasive ductal carcino...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical breast cancer 2016-04, Vol.16 (2), p.113-122.e1
Hauptverfasser:	Jhaveri, Komal, Teplinsky, Eleonora, Silvera, Deborah, Valeta-Magara, Amanda, Arju, Rezina, Giashuddin, Shah, Sarfraz, Yasmeen, Alexander, Melissa, Darvishian, Farbod, Levine, Paul H, Hashmi, Salman, Zolfaghari, Ladan, Hoffman, Heather J, Singh, Baljit, Goldberg, Judith D, Hochman, Tsivia, Formenti, Silvia, Esteva, Francisco J, Moran, Meena S, Schneider, Robert J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antineoplastic Combined Chemotherapy Protocols - pharmacology Biomarkers Biomarkers, Tumor - metabolism Breast Neoplasms - drug therapy Breast Neoplasms - metabolism Breast Neoplasms - pathology Carcinoma, Ductal, Breast - drug therapy Carcinoma, Ductal, Breast - metabolism Carcinoma, Ductal, Breast - pathology Female Follow-Up Studies Hematology, Oncology and Palliative Medicine Humans Immunoenzyme Techniques Inflammatory breast cancer Inflammatory Breast Neoplasms - drug therapy Inflammatory Breast Neoplasms - metabolism Inflammatory Breast Neoplasms - pathology Janus Kinase 2 - metabolism Middle Aged Neoadjuvant Therapy Neoplasm Invasiveness Neoplasm Recurrence, Local - drug therapy Neoplasm Recurrence, Local - metabolism Neoplasm Recurrence, Local - pathology Neoplasm Staging Obstetrics and Gynecology Prognosis Receptor, ErbB-2 - metabolism Receptors, Estrogen - metabolism Receptors, Progesterone - metabolism Resistance to chemotherapy Signal Transduction - drug effects Signaling pathways STAT3 Transcription Factor - metabolism Survival Rate Targeted therapies TOR Serine-Threonine Kinases - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!