Association between Gastroesophageal Reflux Disease and Appendicitis: A Population-Based Case-Control Study

Appendicitis and gastroesophageal reflux disease (GERD) are both prevalent diseases and might share similar pathological mechanisms. The aim of this study was to investigate the association between GERD and appendicitis using a large population-based dataset. This study used administrative claims da...

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Veröffentlicht in:	Scientific reports 2016-03, Vol.6 (1), p.22430-22430, Article 22430
Hauptverfasser:	Kao, Li-Ting, Tsai, Ming-Chieh, Lin, Herng-Ching, Lee, Cha-Ze
Format:	Artikel
Sprache:	eng
Schlagworte:	692/4020/1503/1502/2747 692/499 Adolescent Adult Age Distribution Aged Aged, 80 and over Appendicitis Appendicitis - complications Appendicitis - epidemiology Case-Control Studies Confidence Intervals Female Gastroesophageal reflux Gastroesophageal Reflux - complications Gastroesophageal Reflux - epidemiology Health risk assessment Humanities and Social Sciences Humans Male Middle Aged multidisciplinary Odds Ratio Population studies Population-based studies Prevalence Science Science (multidisciplinary) Taiwan - epidemiology Young Adult
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Zusammenfassung:	Appendicitis and gastroesophageal reflux disease (GERD) are both prevalent diseases and might share similar pathological mechanisms. The aim of this study was to investigate the association between GERD and appendicitis using a large population-based dataset. This study used administrative claims data from the Taiwan Longitudinal Health Insurance Database 2005. We identified 7113 patients with appendicitis as cases, and 28452 matched patients without appendicitis as controls. This study revealed that GERD was found in 359 (5.05%) cases and 728 (2.56%) controls ( p
ISSN:	2045-2322 2045-2322
DOI:	10.1038/srep22430