Euglycemic diabetic ketoacidosis induced by SGLT2 inhibitors: possible mechanism and contributing factors

It is possible that SGLT2 inhibitors trigger euglycemic diabetic ketoacidosis in some patients. Possible mechanism of euglycemic DKA induced by SGLT2 inhibitors is illustrated.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of diabetes investigation 2016-03, Vol.7 (2), p.135-138
Hauptverfasser:	Ogawa, Wataru, Sakaguchi, Kazuhiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Appendicitis Appetite loss Blood Glucose Body mass index Body weight Body weight loss Carbohydrates Carnitine palmitoyltransferase Cerebral infarction Diabetes Diabetes mellitus Diabetic ketoacidosis Diabetic Ketoacidosis - chemically induced Drugs Dyslipidemia Excretion Fatty acids Fatty liver Glucagon Glucose Humans Hyperglycemia Hypoglycemic Agents - adverse effects Hypoglycemic Agents - pharmacology Influenza Insulin Insulin resistance Insulin secretion Ketoacidosis Ketones Liver diseases Metabolic Networks and Pathways - drug effects Metabolism Mitochondria Oxidation Patients Peptides pH effects Pharmaceuticals Secretion Sodium-Glucose Transporter 2 - antagonists & inhibitors Surgery Urine Womens health
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Beschreibung
Zusammenfassung:	It is possible that SGLT2 inhibitors trigger euglycemic diabetic ketoacidosis in some patients. Possible mechanism of euglycemic DKA induced by SGLT2 inhibitors is illustrated.
ISSN:	2040-1116 2040-1124
DOI:	10.1111/jdi.12401