Triple positivity of HBsAg, anti-HCV antibody, and HIV and their influence on CD4+ lymphocyte levels in the highly HIV infected population of Abeokuta, Nigeria

Background: Few studies exist on hospital-based seroprevalence of triple positivity of HIV/HBV/HCV in Nigeria. Objectives: The study aimed at determining the triple positivity of HIV, HBsAg and HCV among HIV-infected individuals in Abeokuta, Nigeria and defining the influence of these triple infecti...

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Veröffentlicht in:	African health sciences 2015-09, Vol.15 (3), p.719-727
Hauptverfasser:	Ogwu-Richard, Sandra Olukemi, Ojo, David Ajiboye, Akingbade, Olusola Abiodun, Okonko, Iheanyi Omezuruike
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged AIDS, ART, HAART, CD4, HIV/HBV/HCV Antiretroviral drugs Antiretroviral Therapy, Highly Active - methods CD4 Lymphocyte Count Enzyme-Linked Immunosorbent Assay Female Hepacivirus - immunology Hepatitis Hepatitis B - complications Hepatitis B - epidemiology Hepatitis B - immunology Hepatitis B Antibodies - blood Hepatitis B Surface Antigens - blood Hepatitis B virus - immunology Hepatitis C - complications Hepatitis C - epidemiology Hepatitis C - immunology Hepatitis C Antibodies - blood HIV Infections - complications HIV Infections - drug therapy HIV Infections - epidemiology HIV Infections - immunology Humans Immune system Male Middle Aged Nigeria - epidemiology Research methodology Seroepidemiologic Studies Serology Statistical analysis Viral infections
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Zusammenfassung:	Background: Few studies exist on hospital-based seroprevalence of triple positivity of HIV/HBV/HCV in Nigeria. Objectives: The study aimed at determining the triple positivity of HIV, HBsAg and HCV among HIV-infected individuals in Abeokuta, Nigeria and defining the influence of these triple infections on CD4+ counts of HIV-infected individuals as antiretroviral therapy improves in Nigeria. Methods: Enumeration of CD4+ levels in 183 HIV-infected persons was done with Partec Flow Cytometer. Seropositivity of HBsAg and anti-HCV antibody was detected with rapid kits. Results: From the result obtained, significance variance (p
ISSN:	1680-6905 1729-0503 1680-6905
DOI:	10.4314/ahs.v15i3.4