Microfluidics as a new tool in radiation biology

Highlights • Microfluidics will provide a new platform technology in radiation research. • Organ-on-a-chip seems to be the most promising in vitro application for radiobiology. • Microfluidics is also used for in vivo application especially for microbeam radiation. • Microfluidics may provide point-...

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Veröffentlicht in:	Cancer letters 2016-02, Vol.371 (2), p.292-300
Hauptverfasser:	Lacombe, Jerome, Phillips, Shanna Leslie, Zenhausern, Frederic
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Automation Automation, Laboratory Biodosimetry markers Biomarkers Biomarkers, Tumor - metabolism Bone marrow Cancer Cell cycle Cytokines Deoxyribonucleic acid DNA Drug dosages Equipment Design Hematology, Oncology and Palliative Medicine Humans Lab-On-A-Chip Devices Methods Microfluidics Microfluidics - instrumentation Microfluidics - methods Neoplasms - metabolism Neoplasms - pathology Neoplasms - radiotherapy Organ-on-a-chip Radiation Dosage Radiation Oncology - instrumentation Radiation Oncology - methods Radiation research Radiobiological models Radiobiology - instrumentation Radiobiology - methods Studies
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Zusammenfassung:	Highlights • Microfluidics will provide a new platform technology in radiation research. • Organ-on-a-chip seems to be the most promising in vitro application for radiobiology. • Microfluidics is also used for in vivo application especially for microbeam radiation. • Microfluidics may provide point-of-care applications for biodosimetry marker assay. • Microfluidics assays are used for early detection and guiding precise radiation therapy.
ISSN:	0304-3835 1872-7980
DOI:	10.1016/j.canlet.2015.11.033