David and Goliath: chemical perturbation of eukaryotes by bacteria

Environmental microbes produce biologically active small molecules that have been mined extensively as antibiotics and a smaller number of drugs that act on eukaryotic cells. It is known that there are additional bioactives to be discovered from this source. While the discovery of new antibiotics is...

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Veröffentlicht in:	Journal of Industrial Microbiology & Biotechnology 2016-03, Vol.43 (2-3), p.233-248
Hauptverfasser:	Ho, Louis K, Nodwell, Justin R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology Antibiotics Bacteria Bacteria - chemistry Biochemistry Bioinformatics Biological Products - chemistry Biological Products - isolation & purification Biological Products - pharmacology Biomedical and Life Sciences Biotechnology Cancer Drugs Eukaryota - chemistry Eukaryota - cytology Eukaryota - drug effects Eukaryota - metabolism Eukaryotes eukaryotic cells Genes Genetic Engineering Genomes Gram-positive bacteria Humans Inorganic Chemistry Kinases Life Sciences Lipids Metabolites Microbiology Molecular Targeted Therapy Natural products Proteins Review Studies Tumors
Online-Zugang:	Volltext
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