What Evidence Is There That Gadobutrol Causes Increasing Signal Intensity within the Dentate Nucleus and Globus Pallidus on Unenhanced T1W MRI in Patients with RRMS?

What Evidence Is There That Gadobutrol Causes Increasing Signal Intensity within the Dentate Nucleus and Globus Pallidus on Unenhanced T1W MRI in Patients with RRMS?

ᅟ Key Points • The study by Stojanov et al does not convincingly support the conclusion that gadobutrol causes higher T1 enhancement in brain on unenhanced MRI • The study by Stojanov et al does not rule out confounding factors • The study by Stojanov et al has limitations in study design

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Bibliographische Detailangaben
Veröffentlicht in:European radiology 2016-03, Vol.26 (3), p.816-817
Hauptverfasser: Agris, Jacob, Pietsch, Hubertus, Balzer, Thomas
Format: Artikel
Sprache:eng
Schlagworte:
Brain
Cerebellar Nuclei
Contrast Media
Diagnostic Radiology
Globus Pallidus
Humans
Imaging
Internal Medicine
Interventional Radiology
Magnetic Resonance Imaging
Medicine
Medicine & Public Health
Neuroradiology
Radiology
Ultrasound
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Zusammenfassung:ᅟ Key Points • The study by Stojanov et al does not convincingly support the conclusion that gadobutrol causes higher T1 enhancement in brain on unenhanced MRI • The study by Stojanov et al does not rule out confounding factors • The study by Stojanov et al has limitations in study design
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-015-4019-2