Evaluation of an Immunochromatographic Lateral Flow Assay (OXA-48 K-SeT) for Rapid Detection of OXA-48-Like Carbapenemases in Enterobacteriaceae

We evaluated an immunochromatographic lateral flow assay to detect OXA-48-like carbapenemases (OXA-48 K-SeT) in Enterobacteriaceae (n = 82). One hundred percent sensitivity and specificity were observed using bacteria recovered from both solid medium and spiked blood culture bottles, and the results...

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Veröffentlicht in:	Journal of clinical microbiology 2016-02, Vol.54 (2), p.471-473
Hauptverfasser:	Wareham, David W, Shah, Rishita, Betts, Jonathan W, Phee, Lynette M, Momin, Muhd Haziq F Abdul
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Proteins - metabolism beta-Lactam Resistance beta-Lactamases - metabolism Carbapenems - pharmacology Enterobacteriaceae Enterobacteriaceae - drug effects Enterobacteriaceae - enzymology Enterobacteriaceae - isolation & purification Enterobacteriaceae Infections - diagnosis Enterobacteriaceae Infections - microbiology Humans Immunoassays Immunochromatography - methods Reagent Kits, Diagnostic Reproducibility of Results Sensitivity and Specificity
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Zusammenfassung:	We evaluated an immunochromatographic lateral flow assay to detect OXA-48-like carbapenemases (OXA-48 K-SeT) in Enterobacteriaceae (n = 82). One hundred percent sensitivity and specificity were observed using bacteria recovered from both solid medium and spiked blood culture bottles, and the results were obtained in
ISSN:	0095-1137 1098-660X
DOI:	10.1128/JCM.02900-15