Efficacy of Anodal Transcranial Direct Current Stimulation is Related to Sensitivity to Transcranial Magnetic Stimulation

Highlights • Substantial inter-individual variability is observed in tDCS studies. • tDCS experiments use a fixed stimulation level, ignoring individual differences in sensitivity to brain stimulation. • TMS thresholds were used as proxy of sensitivity to brain stimulation, and then related to efficacy of tDCS. • Following anodal tDCS, changes in TMS-induced motor evoked potentials were measured. • Efficacy of anodal tDCS was predicted by individual differences in sensitivity to brain stimulation (TMS thresholds).