Optimal Anticoagulation Strategy for Cardioversion in Atrial Fibrillation
For many patients with symptomatic atrial fibrillation, cardioversion is performed to restore sinus rhythm and relieve symptoms. Cardioversion carries a distinct risk for thromboembolism which has been described to be in the order of magnitude of 1 to 3 %. For almost five decades, vitamin K antagoni...
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description | For many patients with symptomatic atrial fibrillation, cardioversion is performed to restore sinus rhythm and relieve symptoms. Cardioversion carries a distinct risk for thromboembolism which has been described to be in the order of magnitude of 1 to 3 %. For almost five decades, vitamin K antagonist therapy has been the mainstay of therapy to prevent thromboembolism around the time of cardioversion although not a single prospective trial has formally established its efficacy and safety. Currently, three new direct oral anticoagulants are approved for stroke prevention in patients with non-valvular atrial fibrillation. For all three, there are data regarding its usefulness during the time of electrical or pharmacological cardioversion. Due to the ease of handling, their efficacy regarding stroke prevention, and their safety with respect to bleeding complications, the new direct oral anticoagulants are endorsed as the preferred therapy over vitamin K antagonists for stroke prevention in non-valvular atrial fibrillation including the clinical setting of elective cardioversion. |
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E: hohnloser@em.uni-frankfurt.de ; Department of Cardiology, Division of Clinical Electrophysiology, JW Goethe University, Frankfurt, Germany</creatorcontrib><description>For many patients with symptomatic atrial fibrillation, cardioversion is performed to restore sinus rhythm and relieve symptoms. Cardioversion carries a distinct risk for thromboembolism which has been described to be in the order of magnitude of 1 to 3 %. For almost five decades, vitamin K antagonist therapy has been the mainstay of therapy to prevent thromboembolism around the time of cardioversion although not a single prospective trial has formally established its efficacy and safety. Currently, three new direct oral anticoagulants are approved for stroke prevention in patients with non-valvular atrial fibrillation. For all three, there are data regarding its usefulness during the time of electrical or pharmacological cardioversion. Due to the ease of handling, their efficacy regarding stroke prevention, and their safety with respect to bleeding complications, the new direct oral anticoagulants are endorsed as the preferred therapy over vitamin K antagonists for stroke prevention in non-valvular atrial fibrillation including the clinical setting of elective cardioversion.</description><identifier>ISSN: 2050-3369</identifier><identifier>ISSN: 2050-3377</identifier><identifier>EISSN: 2050-3377</identifier><identifier>DOI: 10.15420/aer.2015.4.1.44</identifier><identifier>PMID: 26835099</identifier><language>eng</language><publisher>England: Radcliffe Medical Education Ltd</publisher><subject>Anticoagulants ; Cardiac arrhythmia ; Cardioversion ; Diagnostic Electrophysiology & Ablation ; Embolisms ; Mortality ; Patients ; Prevention ; Stroke ; Thromboembolism</subject><ispartof>Arrhythmia & electrophysiology review, 2015-05, Vol.4 (1), p.44-46</ispartof><rights>2015. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the associated terms available at https://www.aerjournal.com/guideline/about-aer#listItem1.8.</rights><rights>Copyright © 2015, Radcliffe Cardiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c424t-25e026caa37c4ab50c06500138d43a5c67e5cd250cb508b3dc6a0f398ad0eeba3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711488/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711488/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26835099$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bushoven, Philipp</creatorcontrib><creatorcontrib>Linzbach, Sven</creatorcontrib><creatorcontrib>Vamos, Mate</creatorcontrib><creatorcontrib>Hohnloser, Stefan H</creatorcontrib><creatorcontrib>Department of Cardiology, Division of Clinical Electrophysiology, JW Goethe University, Theodor-Stern-Kai 7, D 60590 Frankfurt, Germany. E: hohnloser@em.uni-frankfurt.de</creatorcontrib><creatorcontrib>Department of Cardiology, Division of Clinical Electrophysiology, JW Goethe University, Frankfurt, Germany</creatorcontrib><title>Optimal Anticoagulation Strategy for Cardioversion in Atrial Fibrillation</title><title>Arrhythmia & electrophysiology review</title><addtitle>Arrhythm Electrophysiol Rev</addtitle><description>For many patients with symptomatic atrial fibrillation, cardioversion is performed to restore sinus rhythm and relieve symptoms. Cardioversion carries a distinct risk for thromboembolism which has been described to be in the order of magnitude of 1 to 3 %. For almost five decades, vitamin K antagonist therapy has been the mainstay of therapy to prevent thromboembolism around the time of cardioversion although not a single prospective trial has formally established its efficacy and safety. Currently, three new direct oral anticoagulants are approved for stroke prevention in patients with non-valvular atrial fibrillation. For all three, there are data regarding its usefulness during the time of electrical or pharmacological cardioversion. Due to the ease of handling, their efficacy regarding stroke prevention, and their safety with respect to bleeding complications, the new direct oral anticoagulants are endorsed as the preferred therapy over vitamin K antagonists for stroke prevention in non-valvular atrial fibrillation including the clinical setting of elective cardioversion.</description><subject>Anticoagulants</subject><subject>Cardiac arrhythmia</subject><subject>Cardioversion</subject><subject>Diagnostic Electrophysiology & Ablation</subject><subject>Embolisms</subject><subject>Mortality</subject><subject>Patients</subject><subject>Prevention</subject><subject>Stroke</subject><subject>Thromboembolism</subject><issn>2050-3369</issn><issn>2050-3377</issn><issn>2050-3377</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpdUc9LwzAYDaI4mbt7koIXL6353fYijOF0MNhBPYc0TWdG18wkHey_N3NzqKd85Hvv8b33ALhBMEOMYvggtcswRCyjGcooPQNXGDKYEpLn56eZlwMw8n4FIUScIVTiSzDAvCAMluUVmC02waxlm4y7YJSVy76VwdgueQ1OBr3cJY11yUS62titdn6_Ml0yDs5E0tRUzrQHxjW4aGTr9ej4DsH79Olt8pLOF8-zyXieKoppSDHTEHMlJckVlRWDCnIWbyNFTYlkiueaqRrH_7grKlIrLmFDykLWUOtKkiF4POhu-mqta6W7eGkrNi7acDthpRF_N535EEu7FTRHiBZFFLg_Cjj72WsfxNp4paONTtveC5RzTCjDpIzQu3_Qle1dF-2JGGERw48hRhQ8oJSz3jvdnI5BUHxXJWJVYl-VoAIJSiPl9reJE-GnGPIFKkKQhg</recordid><startdate>201505</startdate><enddate>201505</enddate><creator>Bushoven, Philipp</creator><creator>Linzbach, Sven</creator><creator>Vamos, Mate</creator><creator>Hohnloser, Stefan H</creator><general>Radcliffe Medical Education Ltd</general><general>Radcliffe Cardiology</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PIMPY</scope><scope>PKEHL</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201505</creationdate><title>Optimal Anticoagulation Strategy for Cardioversion in Atrial Fibrillation</title><author>Bushoven, Philipp ; Linzbach, Sven ; Vamos, Mate ; Hohnloser, Stefan H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c424t-25e026caa37c4ab50c06500138d43a5c67e5cd250cb508b3dc6a0f398ad0eeba3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Anticoagulants</topic><topic>Cardiac arrhythmia</topic><topic>Cardioversion</topic><topic>Diagnostic Electrophysiology & Ablation</topic><topic>Embolisms</topic><topic>Mortality</topic><topic>Patients</topic><topic>Prevention</topic><topic>Stroke</topic><topic>Thromboembolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bushoven, Philipp</creatorcontrib><creatorcontrib>Linzbach, Sven</creatorcontrib><creatorcontrib>Vamos, Mate</creatorcontrib><creatorcontrib>Hohnloser, Stefan H</creatorcontrib><creatorcontrib>Department of Cardiology, Division of Clinical Electrophysiology, JW Goethe University, Theodor-Stern-Kai 7, D 60590 Frankfurt, Germany. E: hohnloser@em.uni-frankfurt.de</creatorcontrib><creatorcontrib>Department of Cardiology, Division of Clinical Electrophysiology, JW Goethe University, Frankfurt, Germany</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Arrhythmia & electrophysiology review</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bushoven, Philipp</au><au>Linzbach, Sven</au><au>Vamos, Mate</au><au>Hohnloser, Stefan H</au><aucorp>Department of Cardiology, Division of Clinical Electrophysiology, JW Goethe University, Theodor-Stern-Kai 7, D 60590 Frankfurt, Germany. 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For almost five decades, vitamin K antagonist therapy has been the mainstay of therapy to prevent thromboembolism around the time of cardioversion although not a single prospective trial has formally established its efficacy and safety. Currently, three new direct oral anticoagulants are approved for stroke prevention in patients with non-valvular atrial fibrillation. For all three, there are data regarding its usefulness during the time of electrical or pharmacological cardioversion. 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subjects | Anticoagulants Cardiac arrhythmia Cardioversion Diagnostic Electrophysiology & Ablation Embolisms Mortality Patients Prevention Stroke Thromboembolism |
title | Optimal Anticoagulation Strategy for Cardioversion in Atrial Fibrillation |
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