The highest (3600 IU) reported overdose of insulin glargine ever and management

Sir, Insulin glargine (LANTUS ® SOLOSTAR ® ; Sanofi Aventis, Deutschland) - relatively a new medication in the treatment of diabetes mellitus - is a long-acting insulin for meeting the basal insulin requirement with an ongoing effect up to 24 h. [1],[2] In literature, there are small number of cases regarding with overdose use of insulin glargine. In these cases, intensive care physicians should immediately initiate continuous dextrose infusions, and the patients should be monitored closely with frequent blood glucose samples to prevent the risk of prolonged hypoglycemia episodes.