Raman spectroscopy-based identification of nosocomial outbreaks of the clonal bacterium Escherichia coli

DNA-based techniques are frequently used to confirm the relatedness of putative outbreak isolates. These techniques often lack the discriminatory power when analyzing closely related microbes such as E. coli . Here the value of Raman spectroscopy as a typing tool for E. coli in a clinical setting wa...

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Veröffentlicht in:European journal of clinical microbiology & infectious diseases 2016-01, Vol.35 (1), p.83-87
Hauptverfasser: Kusters, J. G., van Leeuwen, W. B., Maquelin, K., Blok, H. E. M., Willemse, H. F. M., de Graaf-Miltenburg, L. A. M., Fluit, A. C., Troelstra, A.
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container_issue 1
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container_title European journal of clinical microbiology & infectious diseases
container_volume 35
creator Kusters, J. G.
van Leeuwen, W. B.
Maquelin, K.
Blok, H. E. M.
Willemse, H. F. M.
de Graaf-Miltenburg, L. A. M.
Fluit, A. C.
Troelstra, A.
description DNA-based techniques are frequently used to confirm the relatedness of putative outbreak isolates. These techniques often lack the discriminatory power when analyzing closely related microbes such as E. coli . Here the value of Raman spectroscopy as a typing tool for E. coli in a clinical setting was retrospectively evaluated.
doi_str_mv 10.1007/s10096-015-2511-x
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subjects Antibiotics
Bacterial Typing Techniques - methods
Bioinformatics
Biomedical and Life Sciences
Biomedicine
Cross Infection - epidemiology
Cross Infection - microbiology
Data analysis
Disease Outbreaks
E coli
Epidemics
Escherichia coli
Escherichia coli - chemistry
Escherichia coli - classification
Escherichia coli - isolation & purification
Escherichia coli Infections - epidemiology
Escherichia coli Infections - microbiology
Hospitals
Humans
Intensive care
Internal Medicine
Medical Microbiology
Nosocomial infection
Original
Original Article
Outbreaks
Retrospective Studies
Spectroscopy
Spectrum analysis
Spectrum Analysis, Raman - methods
title Raman spectroscopy-based identification of nosocomial outbreaks of the clonal bacterium Escherichia coli
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