Measuring and using light in the melanopsin age

Highlights • Photoreceptive retinal ganglion cells (ipRGCs) regulate behavior and physiology. • ipRGCs use melanopsin-dependent intrinsic light responses and rod/cone inputs. • The relative contribution of each photoreceptor to evoked responses is not fully understood. • A method for quantifying lig...

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Veröffentlicht in:	Trends in neurosciences (Regular ed.) 2014-01, Vol.37 (1), p.1-9
Hauptverfasser:	Lucas, Robert J, Peirson, Stuart N, Berson, David M, Brown, Timothy M, Cooper, Howard M, Czeisler, Charles A, Figueiro, Mariana G, Gamlin, Paul D, Lockley, Steven W, O’Hagan, John B, Price, Luke L.A, Provencio, Ignacio, Skene, Debra J, Brainard, George C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cells Circadian rhythm Circadian Rhythm - physiology Humans Light Measurement techniques Neurology Photoreceptor Cells - metabolism Phototherapy - trends Retinal Ganglion Cells - metabolism Rod Opsins - physiology Sleep disorders
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Beschreibung
Zusammenfassung:	Highlights • Photoreceptive retinal ganglion cells (ipRGCs) regulate behavior and physiology. • ipRGCs use melanopsin-dependent intrinsic light responses and rod/cone inputs. • The relative contribution of each photoreceptor to evoked responses is not fully understood. • A method for quantifying light is presented that accounts for complex photoreceptive inputs. • Guidance for those designing architectural and therapeutic lighting is provided.
ISSN:	0166-2236 1878-108X
DOI:	10.1016/j.tins.2013.10.004