Disrupted glucocorticoid—Immune interactions during stress response in schizophrenia

Highlights • Schizophrenia patients did not differ significantly from health controls in magnitude of salivary IL-6 response to a psychological stress task. • Acute cortisol response was inversely related to post-stress IL-6 changes in healthy controls, but the opposite pattern was found in patients...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Psychoneuroendocrinology 2016-01, Vol.63, p.86-93
Hauptverfasser:	Chiappelli, Joshua, Shi, Qiaoyun, Kodi, Priyadurga, Savransky, Anya, Kochunov, Peter, Rowland, Laura M, Nugent, Katie L, Hong, L. Elliot
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antipsychotic Agents - therapeutic use Case-Control Studies Cognition Endocrinology & Metabolism Female Glucocorticoids - metabolism Humans Hydrocortisone - metabolism Interleukin-6 - immunology Male Memory, Short-Term Middle Aged Psychiatry Psychotic Disorders - drug therapy Psychotic Disorders - immunology Psychotic Disorders - metabolism Psychotic Disorders - psychology Saliva - chemistry Schizophrenia - drug therapy Schizophrenia - immunology Schizophrenia - metabolism Schizophrenic Psychology Stress, Psychological - immunology Stress, Psychological - metabolism Stress, Psychological - psychology Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • Schizophrenia patients did not differ significantly from health controls in magnitude of salivary IL-6 response to a psychological stress task. • Acute cortisol response was inversely related to post-stress IL-6 changes in healthy controls, but the opposite pattern was found in patients.
ISSN:	0306-4530 1873-3360
DOI:	10.1016/j.psyneuen.2015.09.010